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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '49d1679bae2290dae0be033a96bda586bcdde7053f4b33c72e7db47a22d3246f' 
  AND token = '7+67v0jFFcN22bw/lHrwFDZF7k1WtfaBfWP1BwXVliE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00752

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}