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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'c7121d73253d53dc1c4ad8c815cec8353076cd923b71ebf1896d186d6f534824' 
  AND token = 'DAxT4Un3OM4555zrYa/H1+1sxFyunmpuXP0XM/txCEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}