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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '250810f64bc929426958e1cb3b9bc094c87ff617c7d705511c10f02e4c4abfcb' 
  AND token = 'RfLcZZKOY9zCOQJTzsF643MWhzoEzNZgZ6WWToKwdOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00756

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}