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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '9e48b049857845398aa37b6c56e018a8119ec49fc7ec03d5747c8a25fe280ac4' 
  AND token = 'zA0YRBqkvs/6N4056mp5NqVSj9hYHiSBbudOk7giUCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00847

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}