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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'f1bcc247e895edc1e1d50943d7f2e9ccaad882b700b83087da39eae16a68289e' 
  AND token = 'RymjS+Bg8ctK4ntS6mXweLOYaZSPtrQ1n2UfoEKl9tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00777

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}