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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '80458262ff8424e2668696e3a61d75f6cf8b6f1f9725e3e74f1db9c5dc52d416' 
  AND token = '0ts1zBnTL61gPzhiLts+0YTHiggQ3RCXTXoeSNLnW1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00791

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}