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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '3a7f683eb686a81120b43b6d29d476da080951a8aa48e1cbfd94fb40b5d0e616' 
  AND token = 'Tct9UGmuF/6PiDbi7kceS07qUZK+tkU2y1I1NUglJ84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00775

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}