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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '6c6d141aa4dbd8901c65434de3654832ca8356b9cd28a4e5b1e4011ffb309410' 
  AND token = '49MWYqKsQOtZYQfnKokEZRuIC+1KCnyf5DwEMWANGRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00773

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}