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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '4b45705b57adfd9ad39cdb977b6f78de3af34e658e26df6c4acaebe44a851110' 
  AND token = 'W1H2HMhqeYVw77y7gjPaeS8fyfaAbYJlOOUOZ4cfZqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00901

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}