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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '44bddb26d9e1be6a32ef4dd411ee21398e169e78b49afbc3c00dd6e782ab8652' 
  AND token = 'IKNJ0zvRo10+5zMzGixO3hX3UgCVO0u1thNJEpr7Soo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00856

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}