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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '28c500bab36bf6548a978710f89a68dc58790c5937af4a52c263c3d42371d225' 
  AND token = 'nZZWeu6AnVuKECKojbPNMFVaSXfqGk5f7bSajuDQWfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00781

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}