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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'a601353ebb65b7c1718be0769b9cc384a11116a1f5e9953f5a3e092a58507737' 
  AND token = 'OGM/TtBroiCQpn/GdofDqYiNSaEurkls8lyYMlT9oCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01472

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}