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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '77c3900bd4804434b0cdafe624cc79835bd4a251332c60bf42bb07f393229e62' 
  AND token = '+6QCRX7lN0Nn5cMnW+N7WYMRu14cLk/uQTj7vi3ZGVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01579

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}