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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'b0b55fd142ea898f729cc5fe7eda3111297129590cdc325910fe378ef8c20890' 
  AND token = 'TKACodvMzT0pkXnEzGesFHMzS8rcXNXFJrvAfeqhAxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01567

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}