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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '8fc8641ac17ee2def2ca7466c7cee8216ea66ab8dddf6b7bae972a872523f4b6' 
  AND token = 'WH66lep9N+QoMvhzOUG/MMRosMt4mhlVynyINjsnaf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00787

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}