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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '944e58681577745c39850caca8e8795349e500258cf2476991b9cde49ead0bf9' 
  AND token = 'u/z/Ji62IaNeKT8gdcrvyBR9e0CFGf9rMpZm0BTfZck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00778

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}