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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '376ce6b940a0ca2ee2d3e9ccbe1cb6576c56c9007b90f80d4711af108a032cf8' 
  AND token = '2wWRWApbCAH5FdS/m0IFDgqglOQ2+fzbwAmL72h+IsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00867

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}