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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '48a2be768076ffde9fca13cafcbbafd61a6edbfa162cb55a55589efaccfa24f5' 
  AND token = 'iXjstVXCxPBEtodIfp0AyoqaynSRZwNeoJnZhY6gPuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00809

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}