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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'b453dc6b9d50160debcee80729f71530e6a79eec12fde4ff312c391a24a62591' 
  AND token = '46BxCLPR/2JqgLpO8rdmxJ3WisfUvF1kAeiz/2zCfNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00769

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}