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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '2206a1b789eaac7de4b190c2253d27f833f31c51ac325a6e7fe3476bea616db1' 
  AND token = 'Kxp9nAuffL//1DCeyj+aPQiW3AbksOy0smT5oufdbGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00782

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}