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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '82faa6ee0f0bfc8442160b6529add4c24713dfb89f6ac1de6902e442e8a7f943' 
  AND token = 'TVg4987434DyumtY+YmAMiAGUtJuwqynE9Q3b957SI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00972

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}