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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '845d2502e53ec13ea139b7a1600e31f8d247cd73be64d3df5da277191c32f76e' 
  AND token = 'uWONiUTR7AJv18uiAATBwKQJbFG/fwEu2C++FIq49Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00847

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}