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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'b701fcc5de78554c5e8f14da0270782a7a75eb878b59ac07310313cb5c0ab8b4' 
  AND token = '+R/2tzrBLNWfIVxTTMHOtl5OH07lNtOH+3rRwGcc6hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00777

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}