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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '8278e3db19476c6a8f96e9ee915860cfe9f46a41f64a55ac4065f9518e65aec6' 
  AND token = 'BuwJPe7jHAcps4ipns1kc4UXRRIwcG02t5g0xBn+ApI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00918

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}