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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '159565206c1362c999bf3cb175adbccb06b17c7fca712981a5d1981ab202d7eb' 
  AND token = 'l9zeKxTSGswhSSsOGdYnSp/R/numeHNFxMcdIIwBIVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00848

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}