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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'bc8f9d833c0e345a099350020053d6e4d41dfe46849e6e9e3768790592d444db' 
  AND token = 'QdolyBzlKRZFzylwcnYE8WkvDy7xfpDRfoQ3UC7Tq2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00750

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}