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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '462a8271456a38e30a18c1414c762c3cd243d8a9e3e09073f86e425115d05dfc' 
  AND token = 'OBNO251wneR2SZybViBXqF2uUhfuijvj64Mp3BZ3YyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00762

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}