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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '46b1f886bc2b0742a67f3bb54db351799c69623e7673eb1fb348729c39adc994' 
  AND token = 'ZJMtBb8FhEdqHK4mhgrOdmMuRh6mNKAO3LPm+Yp65UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00844

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}