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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = 'bed411bce5ed1ce62d72edb4851929edd764bad9b65559204cdb905997e04f6f' 
  AND token = 'lPSR26ORDBnKhuRTTe+qYL4dBOc4hifPqTTkqZQFBBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00825

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}