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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '0d4f842bb8d4ab99006a4ccd8db2086c1a10ace0636790394a985c2109b2e5df' 
  AND token = 'eAIrg54vzcn3+Z8lN2iE0CHbeESeKzJbnUj+MrM/I7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00781

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}