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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '65264c0e486eaa7eb5f0161aeeaad7c7c7253eb70e3e372b6219c4c504b9f913' 
  AND token = 'FAfnH2qaoTB6s9VtxQ9JpxeUR3aau3tbtJZnSOK7+pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01575

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}