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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '780cb088e04b69dc03dfb8d2bbe92f8f5b36963e5607aef33328ffdd6ded5492' 
  AND token = '8v5M37tXT0vyloO4aPZYjWBw3zv0b6Ok13fbt4+NnbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00771

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}