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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '48935625bd6e2b0e113f30caa34a3a2b2bdc1135806b9cc22d77e234e4856293' 
  AND token = '8USIJ709+De8pNfPXkcDWDKoumCqsEc9qDcWr/TZW/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00896

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}