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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '3622e8366c32129f5b95eb282f2b2b17b066b724c8c628ddb7875a8f6b76b3e2' 
  AND token = '65Wy2+Xt4T7gu+JCPRfmrlhyfeAXzOBOI1ff1Tmipjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00775

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}