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SELECT 
  1 
FROM 
  tmall_lock_keys 
WHERE 
  key_id = '2644c2dddc32daef8dd1f451d712f69230dcc37cd96dde6df6ea13348d860b33' 
  AND token = 'JgQs0vHbeXUlK6QfCMZp2vgwGW/nmaTAgAdYUnB/eCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00788

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}